Product Information: The cDNA for Cyno IFN-Alpha 2 was cloned from Cynomolgus (Macaca fascicularis) primary hepatocytes. Two sequences were identified, the first was found to be identical to the putative Rhesus IFN-Alpha 2 (XM_001107516) PBL Cat No. 14110 (Rhesus/Cyno IFN Alpha 2). The second, PBL Cat No. 16100-1 (Cynomolgus IFN Alpha 2 [Ile 16]), may represent an allelic form which differs from the Rhesus/Cyno Alpha 2 sequence by 1 amino acid. This version has Isoleucine at position 16 while the Rhesus/Cyno Alpha 2 has Methionine at position 16. Both forms were identified multiple times from the hepatocytes.
Figure 1: Activity of Cyno IFN Alpha 2 [Ile 16] and Human IFN Alpha A on rhesus cells (LLC-MK2).
Figure 2: Activity of Cyno IFN Alpha 2 [Ile 16] and Human IFN Alpha A on human cells (A549).
This Product is for RESEARCH USE ONLY and is not for sale or use in any commercial kit or for use in the preparation of any commercial antibody. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE, OR USE IN HUMANS.